Aluminium toxicity dissertation

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What are the effects of aluminium on the body?

Of course, specific effects of aluminium are often going to be associated with particular target sites, such as the brain, and the body burden per se may not accurately predict such toxicity.

What is the relationship between aluminium and exposure?

A schematic which explores relationships between exposure, immediate targets mediating exposure, sinks and sources of biologically available aluminium with putative mechanisms of action and finally excretion of aluminium.

How much aluminium are we exposed to daily?

If humans are directly exposed to, for example, only 0.1% of this potential then our current daily exposure equates to 30 mg of aluminium. On a similar basis our exposure to aluminium would have been 1 mg per day in 1950 and will be 100 mg per day by 2050.

Is there any legislation on exposure to aluminium?

It is truly an anomaly that the perceived innocuousness of aluminium in humans has persisted through to the present day and to the extent that there is no legislation whatsoever limiting human's exposure to aluminium.

Last Update: Oct 2021


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